Conducting Polymer Based Nucleic Acid Sensor for Environment Monitoring
نویسندگان
چکیده
Nucleic acid sensor based on polyaniline has been fabricated by covalently immobilizing double stranded calf thymus (dsCT) DNA onto perchlorate (ClO4 ) doped polyaniline (PANI) film deposited onto indium-tin-oxide (ITO) glass plate using 1-(3-(dimethylamino) propyl)3-ethylcarbodiimide hydrochloride (EDC)/N-hydroxyl succinimide (NHS) chemistry. These dsCT-DNA-PANI/ITO and PANI/ITO electrodes have been characterized using square wave voltammetry, electrochemical impedance, and Fourier-transform-infra-red (FTIR) measurements. This disposable dsCT-DNA-PANI/ITO bioelectrode is stable for about four months, can be used to detect arsenic trioxide (0.1 ppm) in 30 s. key words: nucleic acid sensor, electrochemical, polyaniline, perchlorate, arsenic trioxide
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ورودعنوان ژورنال:
- IEICE Transactions
دوره 91-C شماره
صفحات -
تاریخ انتشار 2008